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Convalescent Plasma Transfusions Help COVID-19 Patients

One study conducted at Texas hospitals recently showed convalescent plasma transfusions led to clinical improvement or hospital discharge in 76 percent of coronavirus patients.

The study involved 25 patients with severe coronavirus at the Houston Methodist hospitals from late March to April. They were transfused with convalescent plasma from recovered COVID-19 donors.

Plasma from recovered COVID-19 cases is transfused to critically ill COVID-19 patients, with the hope that the antibodies will help the patient fight or neutralize the disease. Study authors say the treatment method has been used to treat microbial infections for more than 100 years. Other doctors began voicing optimism for the plasma transfusions in COVID-19 patients earlier in the pandemic when some cases improved.

The Houston study was published May 26 in The American Journal of Pathology.

The study's outcomes focused on safety and the potential benefit of transfusing convalescent plasma to patients with severe coronavirus. Noting several other studies that suggest plasma donations are an effective treatment strategy for COVID-19, the Houston reachers wanted to offer more data on initial clinical observations.



“The data indicate that administration of convalescent plasma is a safe treatment option for those with severe COVID-19 disease,” study authors wrote.

A week after transfusion, 36 percent of patients showed clinical improvement. Another seven days later, a total of 76 percent, or 19 patients, improved or were discharged from the hospital.

Study authors described the therapy, which was one transfusion of 300 mL of plasma, as “well-tolerated,” and said that “no transfusion-related adverse events were observed.”

Original article by Fox News.

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For those of you interested in learning more about, COVID-19 Pedagogy author Maureen Sullivan has written the courses COVID-19: A Healthcare Pandemic and COVID-19: A Healthcare Pandemic for Post Acute Care.

COVID-19: A Healthcare Pandemic

The purpose of this educational offering is to familiarize the healthcare professional with the issues surrounding COVID-19, a coronavirus that is currently causing a healthcare pandemic. This novel or new coronavirus was identified last year (2019), and is currently causing increasing numbers of illness and death worldwide. As this viral infection takes a financial, medical, and emotional toll on the worldwide population, it is imperative that all healthcare workers have a basic understanding of the virus, its symptoms, and transmission, and most importantly, what measures can be taken to lower the risk of infection in all areas of work and home.

COVID-19: A Healthcare Pandemic for Post Acute Care

The purpose of this educational offering is to familiarize the healthcare professional with the issues surrounding COVID-19, a coronavirus that is currently causing a healthcare pandemic. This novel or new coronavirus was identified in 2019, and is currently causing illness and death worldwide. As this viral infection takes a financial, medical, and emotional toll on the worldwide population, it is imperative that all healthcare workers have a basic understanding of the virus, its symptoms, and transmission, and most importantly, what measures can be taken to lower the risk of infection in all areas of work and home. The Post Acute Care sector cares for the most vulnerable population and Centers for Medicare and Medicaid Services has specific guidelines for facilities to follow. This course will discuss current treatment options, basic healthcare laws as they relate to public health emergencies, healthcare provider burnout and moral injury as the pandemic persists.

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