Welcome to Pedagogy   |   Sign In

Prolonged Infusion of Beta-lactam Antibiotics in Sepsis Patients

Prolonged infusion of beta-lactam antibiotics in comparison to the intermittent infusion has the theoretical advantage of better patient outcomes.

Introduction: In the current era of relatively scarce antibiotic production and significant levels of antimicrobial resistance, optimization of pharmacokinetics and pharmacodynamics of antibiotic therapy is mandatory. Prolonged infusion of beta-lactam antibiotics in comparison to the intermittent infusion has the theoretical advantage of better patient outcomes. Apparently, conflicting data in the literature possibly underestimate the benefits of prolonged infusion of antibiotic treatment.

Areas covered: We provide our perspective on the subject based on our experience and by critically evaluating literature data.

Expert opinion commentary: In our opinion, the available data are suggestive of the beneficial role of prolonged infusion of beta-lactams in regard to piperacillin/tazobactam and carbapenems after administering a loading dose. While more data from randomized controlled trials are necessary to solidify or negate the evident benefits of prolonged infusion of the aforementioned antibiotics, clinicians should strongly consider this mode of administration of relevant antibiotics, especially in patients with severe infections.

Original article by IV Team.

In this ever-changing landscape, nurses need working knowledge of the antimicrobial agents available, and competency to infuse these medications in all the various administration systems in use today. This 5 course package discusses IV antibiotics, antifungals, antivirals, ß-lactams, and glycopeptides. 
These courses combined offer 8 contact hours. The student will receive a "Certificate of Successful Completion" for each course upon passing the exam with a score of 80% or greater.

This five course package offers a 10% discount off our regular course price offerings.

Click here to view the package!
Pedagogy Newsletter
Subscribe to Pedagogy's Quarterly Newsletter

Subscribe


Copyright © 2020 Pedagogy, Inc. All Rights Reserved.



Powered by Kentico