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Pamela Clark

Pamela Clark, CRNI, is a Nurse Manager for Healix, a leader in the field of parenteral services. She has more than 28 years of experience in infusion therapy and infusion education with both licensed nurses and patients. Her experience spans multiple infusion settings including: acute care, long-term care, home infusion, and ambulatory infusion care. She also has experience in oncology and oncology research.

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Class Accreditation
All states (with the exception of Hawaii) recognize our courses for accredited continuing nursing education, CNE, contact hours.
This course is accredited by the following boards:
Provider approved by the California Board of Registered Nursing, Provider # CEP 15467.
Provider approved by the Arkansas, District of Columbia, Florida, Georgia , South Carolina Boards of Nursing through CE Broker, CE Provider #: 50-13256.  
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Caring for Patients with Bleeding Disorders

Contact Hours: 2.5
Cost: $25.00
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Caring for Patients with Bleeding Disorders
This instructional course has been designed for healthcare clinicians administering and/or caring for the patient with a bleeding disorder. Although the patient may receive long-term care at a physician’s office or Hemophilia Treatment Center, day-to-day care occurs at home, school, work, camp, etc. All clinicians involved in infusing antihemophilic agents and those caring for patients receiving these medications need a working knowledge of the diagnoses for which they are given, proper storage, preparation and administration, and disposal, as well as appropriate interventions, and the psychological implications of having these diseases and receiving treatment for them. Education-related specifically to bleeding disorders is crucial to the safe and effective care of these patients.

State Boards of Nursing have varying positions on the role of the LPN/LVN in the administration of infusion therapy, including the administration of antihemophilic agents. A link to each state board of nursing is listed here. Competency requirements are obtained and maintained through the nurse’s employer, facility or institution. 


Upon completion of this course, the participant should be able to:

1. Describe the symptoms of bleeding disorders
2. Explain the factor deficiencies in Hemophilia A, Hemophilia B, and von
    Willebrand disease
3. Describe R.I.C.E
4. Recognize antifibrolytic agents used to treat bleeding disorders
5. Describe at least two ramifications of bleeding disorders presented in this course
6. Identify at least three treatments used for patients with inhibitors
7. Identify at least two potential future treatments for bleeding disorders and their
    potential advantages over current treatments


Chapter 1: Introduction
• Definition
• Symptoms
• History
• The coagulation cascade

Chapter 2: More Common Bleeding Disorders
• Factor VIII deficiency
• Factor IX deficiency
• Von Willebrand disease

Chapter 3: Treatment
• R.I.C.E.
• Prophylactic factor replacement
• Other medications/substances

Chapter 4: Less Common Factor Deficiencies
• Factor I
• Factor II
• Factor V
• Combined factor V/VIII
• Factor VII
• Factor X
• Factor XI
• Factor XII
• Factor XIII

Chapter 5: Ramifications of Bleeding Disorders
• Joint damage
• Pain
• Health-related quality of life
• Financial impact
• Social and emotional impact

Chapter 6: Inhibitors
• Definition
• Measuring inhibitors
• Treatment for patients with inhibitors
 Bypassing products
 PCCs and APCCs
 Recombinant Factor VIIa
 Other medications
 Plasmapheresis
 Immune tolerance induction

Chapter 7: The Future of Bleeding Disorder Treatment
• Fitusiran
• Concizumab
• B-domain depleted porcine FVIII
• Gene therapy
• Improved FVIII & FIX half-life

Chapter 8: The Role of the Nurse

Chapter 9: Treatment Administration

Chapter 10: References

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